Are you really listening to your body?

By Anita Barnes

Listening to your body can be something as simple as going to bed when you are tired, stop eating before you are overstuffed, or releasing a yoga posture when you’ve gone beyond your edge.  It can also involve more serious things, like preventing your stress levels from exploding into chest pain by saying no, averting an acute pain situation or chronic disease by knowing when to slow down, and respond to pain or discomfort in your body.  

For me, the essence of yoga is about listening to your body, mind and emotions and honouring where they are at, because this changes from day to day, hour to hour, minute to minute.  This listening may involve noticing how your body feels in a particular pose-are your muscles tight, are you feeling a sense of release?  How is your breath-do you notice times when you are holding it or breathing faster than you should?  How are your emotions-what’s coming up for you; sadness, anger, impatience, or boredom?  

I learn so much about myself while on my yoga mat.  Through stillness, movement and breath, I have increased awareness of where I’m holding muscle tension and how my nervous system is doing.  This mindfulness helps me move through negative emotions, practice self-compassion and often find sweetness underneath the negativity.  

Our body and emotions are always communicating, and sometimes it’s very subtle, and unfortunately, we often ignore it.  This has happened to me twice in the last year, and honestly, I should have known better.  In the spring, during the first lockdown – (what # are we at now?) I continued with my weight workout because my gym was closed.  I used light weights and after a few weeks felt they were too light and increased the amount.  I started to notice an occasional throbbing pain in my left triceps.  I ignored this and continued to ignore it, not making the connection that the heavier weights were taxing my muscles.  One night I was awoken by the most excruciating pain, exactly where I felt the original throbbing pain, and it was radiating up to my neck and down to my wrist.   Luckily, I was able to see my physiotherapist and chiropractor for treatment, and they felt the pain was connected to an aggravated radial nerve.  My doctor prescribed me an anti-inflammatory, and I felt better after the first treatment; however, it took several months until I fully recovered. 

You think this would have been a massive wake up call for me to pay attention to subtle changes in my body-the whispers.  Nope.  Since the recent lockdown, state of emergency, whatever we’re at these days, I committed to going for a long walk or hike every single day because my spirit needed this connection to nature.  After a few longer hikes of 2-3 hours through a local conservation area, I noticed a pain in my right glute.  It wasn’t severe pain and didn’t last long, so it was easy to brush off.  However, it did happen at least 4-5 times, and I completely ignored it, and just over a week ago, I paid for this BIG TIME!!!!   

After an active day on January 15th, I noticed a pain in my right hip flexor, went to bed, but didn’t stay long because the pain became too intense.  By Saturday afternoon the pain had increased with a vengeance, and I didn’t sleep on Saturday night and woke my husband up at 3 am on Sunday informing him that he had to take me to emergency because I was in that much pain.  At the ER they ruled out a few things and thought that diagnosis was piriformis syndrome-irritation of the piriformis muscle.  They suggested rest, anti-inflammatories, extra-strength Tylenol and physiotherapy to get back on track.  The pain wasn’t being managed, and on Tuesday morning, I had to go to the ER once again because the pain became so severe that I couldn’t walk.  This time they focused on pain management and gave me morphine via IV and a script.  The pain subsided, and I was able to walk and go home.  

By this time, I hadn’t slept for 4 nights and saw my physiotherapist for the first time.  He performed a full assessment and didn’t think I had piriformis syndrome and felt that my joint and muscles were functioning well.  He thought that I might have overdone it with my hikes and aggravated some muscles and nerves.  

I continued with the pain management meds and physiotherapy, and last Saturday afternoon, I noticed that the pain had left entirely.  I haven’t had any pain since and still have no idea what caused it, but have some ideas.  I believe that my enthusiastic hikes irritated the muscles and nerves in my right hip, and I had plenty of warning that something was up.  

I’m so grateful to be pain-free and have the most profound compassion and empathy for anyone dealing with chronic pain.   I honestly don’t know how anyone deals with it. 

I don’t want to go through something like this again, and I’ve learned my lesson about the importance of listening to my body, not just on my yoga mat, but always.  

Our body, breath and emotions are always communicating to us and sending us messages.  They usually start as little whispers, and if you don’t pay attention, your body will yell at you loud and clear and force you to listen. 

Off the yoga mat, it’s essential to take time throughout your day to slow down, be still and tune in.  How does your body feel?  Do an emotional check-in.  Honour your body, and give it the attention and nurturing that it deserves.  Trust your body,  its’ wisdom and healing abilities.  

Be well.

Anita

Source: https://countyyogaloft.ca/blog/mijpjcfyqxydger4435o02oej6q2zl

Link:https://peacelilysite.com/2025/12/05/are-you-really-listening-to-your-body/

CytoMed, a Singapore Biotech, Revolutionizes Cancer Treatment Using Donor Immune Cells

Ethan Stone Contributor

In Singapore, one biotech company is changing how we approach cancer treatment. CytoMed Therapeutics (NASDAQ: GDTC), just launched its ANGELICA clinical trial, to fundamentally change how we make cancer treatments available to patients worldwide. Building on the success of CAR T-cell therapy in treating blood cancers, they’re taking things to the next level by tackling a broader range of cancers while making the whole process quicker, easier, and more affordable for patients. 

“Think of it as training a versatile army of super-soldiers to fight cancer,” explains Peter Choo, Chairman of CytoMed. “Traditional CAR T-cell therapy takes soldiers from the patient’s own body, but these soldiers are often weakened because the patient has already been through multiple rounds of chemotherapy. Instead, we’re recruiting healthy soldiers from disease-free, well donors and equipping them with special targeting systems to hunt down cancer cells.” 

Manufacturing cells for Singapore’s ANGELICA trial in CytoMed’s cGMP lab

This “targeting system” is an artificial protein called a chimeric antigen receptor (CAR) that helps immune cells recognize and attack cancer cells. While current CAR T-cell therapies require extracting and modifying a patient’s own cells – a process that can take weeks and cost hundreds of thousands of dollars – CytoMed’s approach uses healthy donor cells that could be available “off-the-shelf” when unrelated patients need them simplifying logistics. 

Another innovation is its versatile platform to weaponize the immune cells. Different targeting systems can be added to equip these soldiers with combinational therapies such as antibodies. 

The Power of Rare Immune Cells 

At the heart of CytoMed’s breakthrough is something extraordinary – a rare warrior in our immune system called gamma-delta T cells. These hidden gems are like needles in a haystack, making up just a tiny fraction – less than 5% – of all T cells flowing through our blood. But don’t let their rarity fool you.  

These cells are nature’s own cancer-fighting specialists, and here’s what makes them really special: when transferred from a donor to a patient, they’re incredibly smart about their attacks, targeting cancer while leaving healthy tissue alone. The company has developed proprietary technology to multiply these rare cells in the laboratory, making them viable for treatment.

The contrast with traditional cell therapies is striking: while current treatments are like custom-building a car for each patient – a time-consuming and expensive process – CytoMed’s approach is focused on having treatments ready “off-the-shelf,” similar to cars available at a dealership. This could make treatment both more timely and significantly more cost-effective for patients. 

The ANGELICA Trial: A New Hope 

CytoMed’s potent hybrid of the human body’s two immune cells, NK & T cells, derived from induced pluripotent stem cells.

The ANGELICA trial, now treating patients in Singapore’s National University Hospital, represents a major step forward in cancer treatment. The trial focuses on various types of cancer that are particularly challenging to treat, including solid tumors and involves patients whose cancers have proven resistant to standard treatments. 

Charting New Territory in Cancer Therapy 

What makes CytoMed’s approach truly remarkable is how far-reaching it could be. While current CAR T-cell treatments have been a game-changer for blood cancers like leukemia and lymphoma, they’ve hit a wall when it comes to other types of cancer. That’s where CytoMed is breaking new ground – their technology shows promise in fighting more than 20 different types of cancer, from breast to lung, liver to ovaries. 

This isn’t just a win for cancer treatment – it’s a proud moment for Singapore’s biotech scene. Born in 2018 from Singapore’s prestigious A*STAR research agency, CytoMed is showing the world that Asian biotech companies aren’t just following trends – they’re setting them. They’re writing a new chapter in cancer treatment innovation. 

But they’re not stopping there. The company is pushing boundaries even further by developing a powerful new weapon against cancer. They’re creating a hybrid cell that combines the best of both worlds – Natural Killer (NK) cells and gamma delta T cells, complete with all their natural cancer-fighting tools. Think of it as creating the ultimate cancer-fighting super cell by merging two of our body’s most efficient defenders. 

Beyond Cancer: Expanding into Longevity Research 

Looking ahead, CytoMed is already exploring ways to expand the use of its technology. In a strategic move that broadens its therapeutic reach, the company acquired a licensed cord blood bank in September 2024, giving them access to naive cord blood – a rare and expensive raw material crucial for developing new treatments. Through its subsidiary LongevityBank, the company plans to research and develop cord blood-derived cells that could treat autoimmune diseases and promote longevity, extending their impact beyond cancer treatment. 

This expansion into regenerative medicine opens up new possibilities for treating a wider range of diseases and conditions. The availability of cord blood provides CytoMed with valuable resources for developing innovative therapies that could address multiple medical challenges. 

A Global Vision for Accessible Treatment 

The company is actively pursuing international collaborations to develop new therapeutic approaches while working to make treatments more affordable and accessible to patients worldwide. Their focus on cost-effective manufacturing and efficient production processes could help bring advanced cell therapies within reach of more patients globally. These cells are inexpensive, streamlined for manufacturing, and easy to ship internationally while retaining high cell viability. 

If successful, their “off-the-shelf” approach to cell therapy could represent a major advance in cancer treatment, potentially offering hope to patients who have exhausted other options. With the ANGELICA trial now underway, this marks an important step forward in making advanced cancer treatments more accessible to those who need them most. As CytoMed continues to innovate and expand its therapeutic offerings, it’s positioning itself at the forefront of a new era in personalized targeted medicine, one where cutting-edge treatments are both effective and accessible to patients around the world. 

For more information about CytoMed and its unique approach to cancer treatment, visit https://www.cytomed.sg/ 

Source: https://www.usatoday.com/story/special/contributor-content/2025/01/06/cytomed-a-singapore-biotech-revolutionizes-cancer-treatment-using-donor-immune-cells/77355978007/