CytoMed, a Singapore Biotech, Revolutionizes Cancer Treatment Using Donor Immune Cells

Ethan Stone Contributor

In Singapore, one biotech company is changing how we approach cancer treatment. CytoMed Therapeutics (NASDAQ: GDTC), just launched its ANGELICA clinical trial, to fundamentally change how we make cancer treatments available to patients worldwide. Building on the success of CAR T-cell therapy in treating blood cancers, they’re taking things to the next level by tackling a broader range of cancers while making the whole process quicker, easier, and more affordable for patients. 

“Think of it as training a versatile army of super-soldiers to fight cancer,” explains Peter Choo, Chairman of CytoMed. “Traditional CAR T-cell therapy takes soldiers from the patient’s own body, but these soldiers are often weakened because the patient has already been through multiple rounds of chemotherapy. Instead, we’re recruiting healthy soldiers from disease-free, well donors and equipping them with special targeting systems to hunt down cancer cells.” 

Manufacturing cells for Singapore’s ANGELICA trial in CytoMed’s cGMP lab

This “targeting system” is an artificial protein called a chimeric antigen receptor (CAR) that helps immune cells recognize and attack cancer cells. While current CAR T-cell therapies require extracting and modifying a patient’s own cells – a process that can take weeks and cost hundreds of thousands of dollars – CytoMed’s approach uses healthy donor cells that could be available “off-the-shelf” when unrelated patients need them simplifying logistics. 

Another innovation is its versatile platform to weaponize the immune cells. Different targeting systems can be added to equip these soldiers with combinational therapies such as antibodies. 

The Power of Rare Immune Cells 

At the heart of CytoMed’s breakthrough is something extraordinary – a rare warrior in our immune system called gamma-delta T cells. These hidden gems are like needles in a haystack, making up just a tiny fraction – less than 5% – of all T cells flowing through our blood. But don’t let their rarity fool you.  

These cells are nature’s own cancer-fighting specialists, and here’s what makes them really special: when transferred from a donor to a patient, they’re incredibly smart about their attacks, targeting cancer while leaving healthy tissue alone. The company has developed proprietary technology to multiply these rare cells in the laboratory, making them viable for treatment.

The contrast with traditional cell therapies is striking: while current treatments are like custom-building a car for each patient – a time-consuming and expensive process – CytoMed’s approach is focused on having treatments ready “off-the-shelf,” similar to cars available at a dealership. This could make treatment both more timely and significantly more cost-effective for patients. 

The ANGELICA Trial: A New Hope 

CytoMed’s potent hybrid of the human body’s two immune cells, NK & T cells, derived from induced pluripotent stem cells.

The ANGELICA trial, now treating patients in Singapore’s National University Hospital, represents a major step forward in cancer treatment. The trial focuses on various types of cancer that are particularly challenging to treat, including solid tumors and involves patients whose cancers have proven resistant to standard treatments. 

Charting New Territory in Cancer Therapy 

What makes CytoMed’s approach truly remarkable is how far-reaching it could be. While current CAR T-cell treatments have been a game-changer for blood cancers like leukemia and lymphoma, they’ve hit a wall when it comes to other types of cancer. That’s where CytoMed is breaking new ground – their technology shows promise in fighting more than 20 different types of cancer, from breast to lung, liver to ovaries. 

This isn’t just a win for cancer treatment – it’s a proud moment for Singapore’s biotech scene. Born in 2018 from Singapore’s prestigious A*STAR research agency, CytoMed is showing the world that Asian biotech companies aren’t just following trends – they’re setting them. They’re writing a new chapter in cancer treatment innovation. 

But they’re not stopping there. The company is pushing boundaries even further by developing a powerful new weapon against cancer. They’re creating a hybrid cell that combines the best of both worlds – Natural Killer (NK) cells and gamma delta T cells, complete with all their natural cancer-fighting tools. Think of it as creating the ultimate cancer-fighting super cell by merging two of our body’s most efficient defenders. 

Beyond Cancer: Expanding into Longevity Research 

Looking ahead, CytoMed is already exploring ways to expand the use of its technology. In a strategic move that broadens its therapeutic reach, the company acquired a licensed cord blood bank in September 2024, giving them access to naive cord blood – a rare and expensive raw material crucial for developing new treatments. Through its subsidiary LongevityBank, the company plans to research and develop cord blood-derived cells that could treat autoimmune diseases and promote longevity, extending their impact beyond cancer treatment. 

This expansion into regenerative medicine opens up new possibilities for treating a wider range of diseases and conditions. The availability of cord blood provides CytoMed with valuable resources for developing innovative therapies that could address multiple medical challenges. 

A Global Vision for Accessible Treatment 

The company is actively pursuing international collaborations to develop new therapeutic approaches while working to make treatments more affordable and accessible to patients worldwide. Their focus on cost-effective manufacturing and efficient production processes could help bring advanced cell therapies within reach of more patients globally. These cells are inexpensive, streamlined for manufacturing, and easy to ship internationally while retaining high cell viability. 

If successful, their “off-the-shelf” approach to cell therapy could represent a major advance in cancer treatment, potentially offering hope to patients who have exhausted other options. With the ANGELICA trial now underway, this marks an important step forward in making advanced cancer treatments more accessible to those who need them most. As CytoMed continues to innovate and expand its therapeutic offerings, it’s positioning itself at the forefront of a new era in personalized targeted medicine, one where cutting-edge treatments are both effective and accessible to patients around the world. 

For more information about CytoMed and its unique approach to cancer treatment, visit https://www.cytomed.sg/ 

Source: https://www.usatoday.com/story/special/contributor-content/2025/01/06/cytomed-a-singapore-biotech-revolutionizes-cancer-treatment-using-donor-immune-cells/77355978007/

8 After-Dinner Rituals That Can Help In Digestion And Prevent Bloating

By incorporating these simple post-meal rituals, you can support your digestive system, alleviate discomfort, and avoid the dreaded bloating that often follows a big meal. 

Written By Olivia Sarkar| Last Updated: Jan 06, 2025, 04:52 PM IST|Source: Bureau

After enjoying a hearty meal, it’s not uncommon to feel uncomfortable or sluggish. Digestive issues like bloating, indigestion, or an uneasy feeling can linger long after the last bite. Fortunately, there are simple after-dinner rituals that can support your digestion and help prevent bloating, leaving you feeling lighter and more at ease. Below are eight effective practices that can make a world of difference to your digestive health.

1. Take a Gentle Walk
After a meal, taking a light walk can be one of the most beneficial things for your digestive system. A short 10-15 minute stroll helps stimulate the digestive process by encouraging the stomach to empty more quickly, reducing bloating and discomfort. It also promotes the movement of food through the intestines, preventing constipation.

2. Sip Warm Water or Herbal Tea
Drinking warm water or herbal tea, such as peppermint, ginger, or chamomile, can greatly improve digestion. These teas have natural properties that soothe the stomach, reduce bloating, and promote the movement of food through your digestive system. Ginger, in particular, can help reduce nausea and gas, while chamomile works as a calming agent to relax your stomach muscles.

3. Avoid Lying Down Immediately
Though it might feel tempting to lounge on the couch after a large meal, lying down too soon can actually slow down the digestive process. Gravity helps food and acid stay in the stomach, and lying flat can increase the risk of acid reflux and bloating. Wait at least 30 minutes to an hour before reclining to allow your body time to process the food.

4. Practice Deep Breathing
After eating, try engaging in deep breathing exercises. This helps stimulate the parasympathetic nervous system (also known as the “rest and digest” system), encouraging optimal digestion. Deep breathing can also reduce stress, which can otherwise impair digestion and cause bloating or discomfort.

5. Massage Your Abdomen
Gentle self-massage can aid in digestion by stimulating the movement of food through the intestines. Use your fingertips to massage your stomach in a clockwise motion (the direction of digestion) for a few minutes. This simple act can help ease bloating, relieve gas, and promote digestion.

6. Incorporate Probiotics
Probiotics are beneficial bacteria that support gut health and digestion. After dinner, consider consuming foods rich in probiotics, such as yogurt, kefir, or fermented vegetables. Alternatively, a probiotic supplement may help maintain a healthy balance of gut bacteria, reducing bloating and improving overall digestion.

7. Stay Hydrated, But Avoid Over Drinking
Drinking water throughout the day aids digestion, but drinking too much water immediately after a meal can dilute stomach acid, impairing your body’s ability to break down food. Try sipping water in moderation after dinner, but avoid excessive consumption right away. This ensures proper digestive function without overwhelming your stomach.

8. Avoid Carbonated Drinks
Carbonated drinks, including sodas and sparkling water, introduce gas into your stomach, which can lead to bloating. After dinner, it’s best to skip the bubbles. Stick to still water or herbal teas, which are far more conducive to smooth digestion.

Fennel seeds are a natural remedy for boosting digestion. Try chewing some after your meal to see if they work for you. From taking a short walk to sipping herbal tea and massaging your abdomen, these habits can make a significant difference in how you feel after dinner. Your digestive health is a reflection of your lifestyle, so taking small, consistent steps can lead to long-term benefits, allowing you to enjoy your meals without the aftermath of discomfort.

Link:https://peacelilysite.com/2025/01/13/8-after-dinner-rituals-that-can-help-in-digestion-and-prevent-bloating/

Source: https://zeenews.india.com/lifestyle/8-after-dinner-rituals-that-can-help-in-digestion-and-prevent-bloating-2840271.html (This article is intended for your general information only. Zee News does not vouch for its accuracy or reliability.)

Nutrigenomics: Exploring the Science of Genes and Diet

In recent years, nutrigenomics—the scientific study of how genes influence our body’s response to food—has gained significant attention. As research in genetics and nutrition continues to advance, this field is paving the way for more personalized health strategies, particularly in the areas of diet and weight management. Understanding how genes affect our reactions to specific foods provides deeper insights into individual health needs, driving the development of personalized wellness approaches.

At the core of nutrigenomics lies the principle that our genetic makeup plays a crucial role in food metabolism. For instance, some individuals may be genetically predisposed to metabolize carbohydrates more efficiently, while others tend to store fat more easily. These insights empower health professionals to design customized dietary plans based on genetic testing rather than relying on generalized nutritional recommendations.

Recent studies have shown that genetic variations can influence how nutrients are absorbed, how efficiently the body burns calories, and even how hunger is experienced. For example, specific variations in the FTO gene have been linked to a higher risk of obesity, as some individuals gain weight more easily due to the way their bodies process food. Similarly, variations in genes like PPARG can impact fat metabolism, further emphasizing the potential of personalized nutrition strategies based on genetic data.

Nutrigenomics introduces a revolutionary approach to weight management. Traditional diets often follow a “one-size-fits-all” model, which may not be effective for everyone. By using genetic data, nutritionists and health experts can develop personalized dietary plans tailored to an individual’s metabolic needs, resulting in more effective weight management.

For example, genetic testing can reveal a person’s sensitivity to fats or carbohydrates, guiding the ideal macronutrient balance for their body. If someone’s genetic profile indicates a higher risk of insulin resistance, a low-glycemic diet may be recommended to help prevent blood sugar spikes and support weight loss. This tailored strategy often proves more effective than generic diets that overlook individual differences.

The Advantages of Personalized Diet Plans

Nutrigenomics brings a significant advantage to dietary planning: personalization. Rather than relying on generalized advice or fleeting diet trends, nutrigenomics empowers individuals to approach health management scientifically. By integrating genetic testing with dietary adjustments, people can achieve better health outcomes and a deeper understanding of their own bodies.

Key benefits of personalized diets include:

  • Improved Metabolic Health: Tailored diets help optimize the body’s ability to process food and maintain a healthy weight.
  • Precise Nutrient Recommendations: Instead of guessing which foods are most beneficial, personalized nutrition ensures individuals receive the nutrients their body specifically needs.
  • Sustainable Weight Management: Nutrigenomics-based diets promote long-term healthy habits by aligning with genetic predispositions rather than short-term trends.

Additionally, nutrigenomics may support preventive health strategies. Genetic testing can identify predispositions to conditions such as heart disease, diabetes, or nutrient deficiencies, allowing individuals to make proactive dietary changes for long-term wellness.

The future of health management is becoming increasingly personalized, with nutrigenomics at the forefront of this transformation. As the field continues to evolve, more health centers are likely to offer genetic testing services to help individuals create personalized nutrition and wellness plans. This data-driven approach reflects a broader trend where people are empowered to take greater control of their health through scientific insights.

While the potential of nutrigenomics is promising, it remains a developing science. Experts emphasize the need for further research to fully understand the complex relationship between genes and diet. Additionally, as the field matures, ethical considerations and privacy concerns must be carefully addressed to ensure individuals are fully informed and protected when sharing their genetic data.

Nutrigenomics represents a powerful fusion of genetic science and nutrition, offering the potential for health strategies tailored to individual genetic profiles. This emerging science can help design diets that promote optimal weight loss, improve metabolic health, and prevent chronic illnesses.

Though still in its early stages, nutrigenomics has the potential to revolutionize health management, making weight control and wellness strategies more effective and sustainable. As research continues to expand, genetic testing could become a key tool in unlocking healthier, more personalized lifestyles for everyone.

Link:https://peacelilysite.com/2025/01/07/nutrigenomics-exploring-the-science-of-genes-and-diet/

Source: https://worldreporter.com/nutrigenomics-tailoring-health-based-on-genes/?fbclid=IwZXh0bgNhZW0CMTAAAR3NXfx9dzeIsmcSiP248IMGxMkppa2gMAEtjuZOgMr7pyU1EaMqk5e5Aio_aem_eY5AmQ5X9nw8JxIaQeZaBg

Virginia Satir: A Master of Family Therapy and the Healing Power of Her Words

When I Am Strong Enough Inside

Virginia Satir (1916–1988) was a trailblazer in the field of family therapy, earning worldwide recognition as a distinguished psychotherapist and one of America’s most influential family therapists. Dubbed “everybody’s family therapist” by Human Behavior magazine, Satir devoted her life to uncovering the complexities of human relationships and exploring the essence of what it means to be human. Her groundbreaking principles for fostering effective family communication continue to be revered and applied by professionals across the globe.

Satir’s legacy extends beyond therapy rooms. Her poetic insights capture the depth of her understanding of human nature and emotions. One of her most touching poems, “When I Am Strong Enough Inside,” serves as a mirror reflecting our inner strength and vulnerability. These verses remind us that the negative voices within us can often overshadow our resilience. However, by engaging with empowering words like hers, we can nurture psychological flexibility and cultivate a more compassionate perspective toward ourselves and others. Here is an excerpt from her poem that encapsulates her profound messag.

When I Am Strong Enough Inside

When I’m strong enough inside,
You blame me,
I feel your pain;
You flatter me,
I see you need approval;
You’re crazy,
I understand your vulnerability and fear;
You interrupt,
I know how much you want to be seen.

When I’m strong enough inside,
I no longer defend,
All the forces,
Free flow between us.
Grievance, depression, guilt, sadness, anger, pain,
When they flow freely.
I feel warm in sorrow,
Find strength in anger,
See hope in pain.

Screenshot

When I’m strong enough inside,
I will not attack.
I know,
When I stop hurting myself,
Then no one can hurt me.
I lay down my arms,
Open heart,
When my heart softens,
In love and compassion,
Meet you bright and warm.

Originally, let the heart strong,
All I need is,
Seeing myself,
Accept what I can’t do,
Appreciate what I’ve done.
And believe,
Through this journey,
Can live out their own, bloom their own.

In these lines, Satir masterfully conveys her belief in the transformative power of understanding the reasons behind others’ actions. Instead of reacting with judgment, she calls on us to see the humanity in others, even when their behavior is challenging.

Her poem continues with a heartfelt reminder that by releasing our own emotions—be it anger, sadness, or guilt—we can uncover strength, warmth, and hope. She encourages us to let go of self-defensiveness, to embrace compassion, and to see ourselves and others with clarity and acceptance.

When I encountered this poem, I was struck by Satir’s tender view of humanity. It eloquently sheds light on behaviors we often judge harshly—blaming, seeking approval, over-rationalizing, or interrupting. Yet, rather than condemning these actions, she invites us to see the vulnerability and pain behind them. This perspective challenged me to think: if my heart were stronger, if I could move beyond my own wounds, perhaps I too could approach the world with such gentle understanding.

Satir’s poem inspires a transformative journey of self-awareness and growth. To build inner strength, she suggests we:

  • See ourselves as we truly are, without judgment.
  • Accept our imperfections with kindness.
  • Appreciate our progress and achievements.
  • Trust in our ability to live authentically and bloom fully.

Her words serve as both a reminder and an invitation—to embrace our humanity, nurture our resilience, and extend the same understanding to others.

Even today, Virginia Satir’s work continues to inspire people to heal, connect, and thrive. Through her profound poetry and her legacy as a master therapist, she reminds us that inner strength and compassion are at the heart of meaningful relationships and a fulfilling life.

Link:https://peacelilysite.com/2024/11/12/virginia-satir-a-master-of-family-therapy-and-the-healing-power-of-her-words/

People who stay joyful in their 70s and beyond usually adopt these 9 daily habits

Photo by RDNE Stock project on Pexels.com

by Lachlan Brown | July 18, 2024, from GlobalEnglishEditing

There’s a significant contrast between simply aging and aging joyfully.

This difference often boils down to habits. While some folks let the years weigh them down, others seem to dance through their 70s and beyond with a smile on their face.

Those who age joyfully are not just lucky. They adopt certain daily habits that keep them buoyant and full of life.

I’ve noticed that there are some key habits that these joyful individuals share. And, if you’re anything like me, you’ll want to know what these habits are.

Ahead are nine daily habits typically adopted by those who stay joyful in their 70s and beyond.

1) They embrace change

When it comes to aging joyfully, adaptability is key.

Those in their 70s and beyond who continue to thrive are often those who have mastered the art of embracing change.

Whether it’s technology, changing family dynamics or shifts in their physical capabilities, they don’t resist. Instead, they adapt and learn.

It’s a simple concept, but not always easy to follow. Change can be daunting. It can be uncomfortable. But it’s also inevitable.

The trick to embracing change lies in shifting your perspective. Instead of viewing change as a threat, view it as an opportunity for growth and new experiences.

The secret? Stay open-minded, stay curious and never stop learning.

This simple daily habit of embracing change can make a world of difference in your outlook on life as you age. It keeps you stimulated, engaged and, most importantly, joyful.

Photo by Andrea Piacquadio on Pexels.com

2) They practice gratitude

One thing I’ve noticed about those who stay joyful in their later years is their capacity for gratitude.

Let me share a personal example. My grandmother, in her 80s, has a daily habit of expressing gratitude. Every morning, she sits by her window with a cup of tea and lists out loud the things she’s thankful for.

Sometimes it’s big things like family and health, sometimes it’s small things like a beautiful sunrise or the sound of birds chirping. The size of the blessing doesn’t matter; what matters is the act of acknowledging it.

I’ve seen how this simple practice has shaped her perspective on life. She focuses on the positive, and this focus radiates joy.

Practicing daily gratitude, I’ve learned from her, is an accessible habit anyone can adopt to age more joyfully.

3) They stay socially active

Contrary to the popular perception of aging as a lonely process, many who remain joyful in their later years do so by maintaining a vibrant social life.

Research in the field of gerontology suggests that social interactions play a crucial role in our mental health and overall well-being as we age.

Staying socially active doesn’t necessarily mean attending grand parties or being constantly on the move. It can be as simple as regular phone calls with a friend, participating in community events, or volunteering for a cause close to your heart.

The key is to stay connected with the world around you. This not only keeps you mentally stimulated but also provides a sense of belonging and purpose, all of which contribute to a joyful mindset.

4) They keep moving

Photo by Marcus Aurelius on Pexels.com

Physical activity is another common habit among those who age joyfully.

They understand the value of keeping their bodies moving. It might be a daily walk around the neighborhood, a yoga class, or even gardening in the backyard. The type of activity doesn’t matter as much as the consistency of being active.

Staying physically active has multiple benefits. It keeps you fit, improves your mood by releasing endorphins (the ‘feel-good’ hormones), and can even enhance cognitive function.

So if you want to join the ranks of those aging joyfully, don’t underestimate the power of movement. Make it a point to stay active and your body, as well as your mind, will thank you for it.

5) They nurture their hobbies

Folks who age with joy tend to have a passion or hobby that they keep alive.

Be it painting, dancing, knitting, or even bird watching, they understand the importance of doing something that brings them genuine happiness. This isn’t about productivity or achievement; it’s about enjoyment.

Having a hobby provides a sense of purpose, keeps the mind engaged, and offers a great way to unwind and relax. It’s a personal space that brings contentment and fulfilment.

So, if there’s something you’ve always wanted to try or an old passion you’ve left behind, now might be the perfect time to pick it up again. It could become your key to aging joyfully.

6) They prioritize relationships

The golden years can be truly golden when filled with meaningful relationships. Those who age joyfully often prioritize their relationships, understanding the deep happiness and comfort that comes from loving and being loved. They make time for their family and friends, cherishing the shared laughs, stories, and even the quiet moments of companionship.

They know that life is filled with ups and downs, and having someone by your side through it all makes the journey more beautiful. These relationships provide emotional security, a sense of belonging, and help to keep loneliness at bay.

Remember, it’s not about having a large number of acquaintances but nurturing a few relationships that are close to your heart. As you age, these bonds can become your greatest source of joy.

7) They practice mindfulness

I’ve seen the power of mindfulness in action. My father, now in his late 70s, has a habit of spending a few minutes every day in quiet reflection.

This isn’t about religious beliefs or meditation practices; it’s about taking a moment to be present, to acknowledge and accept the way things are, without trying to change anything.

On particularly challenging days, he says these moments of mindfulness help him handle stress better, bring clarity to his thoughts, and cultivate a calm demeanor.

By being in the present moment, we can appreciate the beauty of life as it unfolds, even with its imperfections. This sense of acceptance and peace can be a powerful tool for staying joyful as we age.

8) They maintain a balanced diet

Food plays a critical role in our overall well-being, and this is especially true as we age. Those who age joyfully are often mindful of what they eat. They understand that a balanced diet is not just about maintaining physical health, but also about ensuring mental well-being.

They opt for nutritious foods that boost energy levels, enhance mood, and support cognitive function. This doesn’t mean they never indulge in their favorite treats; instead, they aim for a balance that serves both their health and their taste buds.

Eating right can help you feel your best and keep you energized, both of which contribute to a joyful outlook on life.

9) They keep a positive mindset

Above all, those who age joyfully understand the power of a positive mindset.They choose to focus on the good in their lives and in the world around them. They believe in the potential for happiness each new day brings, no matter what challenges it might also carry.

A positive mindset isn’t about ignoring life’s difficulties. It’s about choosing to see beyond them, to find hope and joy even in the hardest of times.

This habit, more than any other, shapes their experience of life as they age. It’s what keeps them resilient, hopeful, and most importantly, joyful.

At the heart of aging joyfully lies a fundamental choice we all have the power to make.

The choice to embrace change, to express gratitude, to stay socially and physically active. The choice to nurture hobbies, prioritize relationships, practice mindfulness, maintain a balanced diet and, above all, keep a positive mindset.

It’s these choices, these daily habits that shape our experience of life as we age. They are the threads that weave together the fabric of a joyful existence in our later years.

Link:https://peacelilysite.com/2024/07/23/people-who-stay-joyful-in-their-70s-and-beyond-usually-adopt-these-9-daily-habits/

Source: https://geediting.com/author/lachlanhackspirit-com/

Healthy childhood diet can ‘keep mind sharp into 70s’ and ward off dementia

From The Guardian

Study is first to track people at different time points in life and finds close link between nutrition and cognitive ability

A healthy diet in childhood can help protect mental sharpness into old age. Photograph: Katarzyna Bialasiewicz/Alamy




A healthy diet earlier in life could help keep you mentally sharp into your 70s, and even ward off dementia, according to research that followed thousands of Britons for seven decades.

While most studies on diet and cognitive ability have focused on people already in or reaching old age, the new review was the first to track people throughout their life – from the age of four to 70 – and suggests the links may start much earlier than previously recognised.

The research adds to a growing body of evidence that a healthy diet could reduce the risk of Alzheimer’s disease and slow age-related cognitive decline. The findings were presented at the annual meeting of the American Society for Nutrition.

“These initial findings generally support current public health guidance that it is important to establish healthy dietary patterns early in life in order to support and maintain health throughout life,” said Kelly Cara, of Tufts University in Massachusetts.

Our findings also provide new evidence suggesting that improvements to dietary patterns up to midlife may influence cognitive performance and help mitigate, or lessen, cognitive decline in later years.”

Cognitive performance can still improve well into middle age, but typically begins to decline after age 65, the researchers said. More serious conditions such as dementia can also develop alongside age-related decline.

For the new research, scientists studied 3,059 adults from the UK who were enrolled as children in a study called the National Survey of Health and Development. Members of the cohort, called the 1946 British Birth Cohort, have provided data on dietary intakes, cognitive outcomes and other factors via questionnaires and tests over more than 75 years.

Researchers analysed participants’ diet at five time points in relation to their cognitive ability at seven time points. Dietary quality was closely linked with trends in cognitive ability, they found.

For example, only 8% of people with low-quality diets sustained high cognitive ability and only 7% of those with high-quality diets sustained low cognitive ability over time compared with their peers.

Cognitive ability can have a significant impact on quality of life and independence as people age, the researchers said. For example, by the age of 70, participants in the highest cognitive group showed a much higher retention of working memory, processing speed and general cognitive performance compared with those in the lowest cognitive group.

In addition, nearly a quarter of participants in the lowest cognitive group showed signs of dementia at that time point, while none of those in the highest cognitive group showed signs of dementia.

While most people saw steady improvements in their diet throughout adulthood, the researchers noted that slight differences in diet quality in childhood seemed to set the tone for later life dietary patterns, for better or worse.

“This suggests that early life dietary intakes may influence our dietary decisions later in life, and the cumulative effects of diet over time are linked with the progression of our global cognitive abilities,” Cara said.

Photo by furkanfdemir on Pexels.com

Study participants who sustained the highest cognitive abilities over time relative to their peers tended to eat more recommended foods such as vegetables, fruits, legumes and whole grains, and less sodium, added sugars and refined grains.

“Dietary patterns that are high in whole or less processed plant-food groups including leafy green vegetables, beans, whole fruits and whole grains may be most protective,” said Cara.

“Adjusting one’s dietary intake at any age to incorporate more of these foods and to align more closely with current dietary recommendations is likely to improve our health in many ways, including our cognitive health.”

Link:https://peacelilysite.com/2024/07/05/healthy-childhood-diet-can-keep-mind-sharp-into-70s-and-ward-off-dementia/

Source: https://www.theguardian.com/society/article/2024/jul/01/healthy-diet-in-childhood-keeps-mind-sharp-into-70s-and-wards-off-dementia

Unveiling the Potency of Willpower: Transforming Lives Through Self-Control

In 1996, a seemingly innocuous experiment conducted by Roy Baumeister and his team at Case Western Reserve University revealed a profound truth about human behavior: the power of will. Their study, which involved tempting participants with chocolate chip cookies only to have them resist and eat radishes instead, demonstrated the finite nature of willpower. This pioneering research laid the groundwork for understanding self-control as a resource that could be depleted, akin to a muscle that fatigues with exertion.

Photo by ROMAN ODINTSOV on Pexels.com

In the first part of the trial, Baumeister kept the 67 study participants in a room that smelled of freshly baked chocolate cookies and then teased them further by showing them the actual treats alongside other chocolate-flavored confections.

While some did get to indulge their sweet tooth, the subjects in the experimental condition, whose resolves were being tested, were asked to eat radishes instead. And they weren’t happy about it.

After the food bait-and-switch, Baumeister’s team gave the participants a second, supposedly unrelated exercise, a persistence-testing puzzle. The effect of the manipulation was immediate and undeniable. Those who ate radishes made far fewer attempts and devoted less than half the time solving the puzzle compared to the chocolate-eating participants and a control group that only joined this latter phase of the study. In other words, those who had to resist the sweets and force themselves to eat pungent vegetables could no longer find the will to fully engage in another torturous task. They were already too tired.

The experiment, while seemingly trivial, yielded crucial insights into the nature of self-regulation. Participants who exerted willpower to resist the tempting chocolates subsequently demonstrated diminished perseverance and performance on a subsequent task. This seminal finding underscored the broader significance of self-control across various domains of life, from mundane daily tasks to more significant challenges.

In the realm of psychology, this research sparked a cascade of studies exploring the multifaceted implications of willpower. It elucidated why individuals are drawn to indulgence after experiencing setbacks, such as seeking solace in retail therapy after heartbreak. Moreover, it provided valuable insights into behavior modification strategies, highlighting the importance of positive reinforcement and habit formation in fostering lasting change.

Understanding the concept of willpower empowers individuals to leverage it effectively in pursuit of their goals. Rather than relying solely on sheer determination, strategic planning plays a pivotal role in optimizing willpower utilization. Timing tasks to align with periods of peak mental and physical energy, such as the morning after a restful night’s sleep, can enhance performance and resilience.

Furthermore, recognizing willpower as a trainable attribute opens avenues for personal growth and development. Cultivating positive habits serves as a cornerstone for strengthening willpower and facilitating sustained behavior change. Initiating small, manageable goals allows individuals to acclimate gradually, paving the way for long-term success. For instance, committing to brief daily rituals, like reading for just two minutes, eating one fruit instead of a cookie, or embarking on a short morning walk, lays the groundwork for more significant lifestyle adjustments. As these habits become ingrained, individuals can incrementally expand their efforts, harnessing the cumulative impact of consistent practice. Joining a group of like-minded individuals can also provide invaluable support in reinforcing positive habits and maintaining motivation.

Additionally, cultivating positive bedtime routines fosters relaxation and promotes quality sleep. Instead of mindlessly scrolling through screens before bed, incorporating a five-minute practice of prayer, meditation, or reflection on gratitude can help unwind the mind and prepare for restorative rest. This intentional shift away from digital distractions not only supports mental well-being but also cultivates a deeper sense of connection with oneself and the present moment.

In essence, comprehending and harnessing the power of willpower is transformative. By integrating strategic approaches to task management, fostering positive habits, and nurturing a supportive network, individuals can unlock their potential for personal and professional fulfillment. As Baumeister’s pioneering research illustrated, the journey towards meaningful change commences with embracing the remarkable capacity of willpower.

Link:https://peacelilysite.com/2024/03/20/unveiling-the-potency-of-willpower-transforming-lives-through-self-control/

Source: https://www.theatlantic.com/health/archive/2012/04/the-chocolate-and-radish-experiment-that-birthed-the-modern-conception-of-willpower/255544

The World Without Complaint: A Journey to Positivity and Gratitude

In a world often overshadowed by negativity, encountering a book that challenges us to break free from the habit of complaining is like a breath of fresh air. “The World Without Complaint” by Well Bowen offers an insightful perspective on the harmful effects of constant complaints and provides practical strategies for fostering a mindset of gratitude and positivity.

We read because we crave insight, resonance, guidance, and growth. Have you ever found yourself caught in a cycle of complaints about the world, life, family, friends, or even strangers? Today, let’s explore some notes from “The World Without Complaint.” This bestselling book has reached readers in 80 countries, urging us to consider how a single book and a simple wristband can transform us from habitual complainers into ambassadors of positivity.


The Marvel of the Wristband
Have you ever participated in a lunchtime gripe session with colleagues or friends, only to find that venting seems to worsen your stress? It’s as if complaining adds fuel to the fire of our worries. The truth is, many of us are oblivious to our own negative attitudes and behaviors. While others may perceive the negativity in our speech, we often fail to recognize it ourselves. But can we change? Absolutely! By wearing the No Complaining wristband and committing to a 21-day challenge, we can become more aware of our complaints, their frequency, and ultimately, how to stop them.

The Secret to a Dream Life
The tool: The No Complaining wristband (or any accessory that reminds you to stay positive, like a fitness tracker). The secret: Consistency. As you practice the 21-day challenge and swap the wristband between your hands, you’ll start paying closer attention to your words and actions. This seemingly insignificant wristband becomes a beacon, helping you identify and release negative emotions you may not have been aware of before.

How to Use the Wristband

  • Wear the wristband on one wrist to start your 21-day journey.
  • When you catch yourself complaining, criticizing, gossiping, or being sarcastic, switch the wristband to the other hand and start over. Each time you switch, you reset your 21-day journey.
  • Keep going.

The Key to Success

  • Move the wristband with each complaint.
  • Keep track of your progress.
  • Focus on your own wristband; don’t worry about others’.
  • Don’t outsmart yourself.

Unconscious Incompetence
Complaining not only distracts us from our true desires but can also harm our health and relationships. Changing just one percent of the world’s population can create a ripple effect of positivity that uplifts everyone. Complaints never attract what we desire; instead, they reinforce what we don’t want. Our thoughts shape our lives, so let’s be fully present, steadfast, and strive to be better versions of ourselves.

Conscious Competence

  • Smile, breathe, take it slow. Our words have power. Changing what we say can change our lives.
  • Criticism and sarcasm are rarely productive. Focus on constructive feedback and encouragement.
  • Plant seeds of positivity in your interactions. Inspire others by embodying the change you wish to see.
  • Transform your mindset from one of complaint to one of gratitude. Every moment is an opportunity to create the life you desire.

Unconscious Competence

  • Transform your tools and methods into personal logic and theory.
  • The best time to plant a tree was ten years ago. The second-best time is now. Believe in your ability to change, and the solutions to all your problems will follow.

Complaining is more than just a fleeting expression of dissatisfaction; it’s a habit that can poison our minds and relationships. Continuously focusing on what’s wrong or lacking in our lives not only perpetuates a cycle of negativity but also reinforces feelings of helplessness and victimhood. Complaining can strain our relationships, as constant negativity can push others away and create a toxic environment.

Moreover, the energy we invest in complaining could be better utilized to find solutions to our problems or to appreciate the blessings we already have. Dwelling on complaints keeps us stuck in a state of discontentment, hindering personal growth and preventing us from fully embracing life’s joys.

Training Yourself to Avoid Complaints
Breaking the habit of complaining requires conscious effort and dedication. Bowen’s book offers practical techniques and exercises to help readers rewire their brains and cultivate a more positive outlook. From mindfulness practices to gratitude journaling, the book provides actionable steps to shift our focus from complaints to appreciation.

One effective strategy is to practice mindfulness and become more aware of our thoughts and emotions. By recognizing the patterns of negativity that lead to complaints, we can interrupt the cycle and choose a more constructive response. Additionally, cultivating a habit of gratitude can help us reframe our perspective and find joy in even the smallest blessings.

The Benefits of Embracing Positivity
Choosing not to complain has numerous benefits that extend beyond our personal well-being. By adopting a positive mindset, we become more resilient in the face of challenges and better equipped to navigate life’s ups and downs. Our relationships thrive in an environment of positivity, fostering deeper connections and mutual support.

Furthermore, a world without complaints has the potential to spark positive change on a larger scale. Imagine if just one percent of the population committed to refraining from complaints— the ripple effects would be profound. Communities would be filled with kindness and compassion, and collective efforts toward solving problems would be more effective and harmonious.

Link:https://peacelilysite.com/2024/03/15/the-world-without-complaint-a-journey-to-positivity-and-gratitude/

The Healing Power of Forgiveness: Unlocking Peace with the REACH Method

In a world often torn apart by conflict and grievances, the importance of forgiveness cannot be overstated. The ability to release resentment and embrace reconciliation is a formidable tool for personal healing and societal harmony. In this blog post, we will explore the REACH Method—a powerful approach to forgiveness created by renowned clinical psychologist Everett Worthington. By delving into each step of the REACH Method—Recall, Empathize, Altruistic gift, Commit, and Hold onto forgiveness—we can learn how forgiveness, under the guidance of Worthington’s methodology, has the potential to bring about positive change, even in the most challenging circumstances.

Recall the Hurt:

The first step in the REACH Method is to Recall the Hurt. It involves acknowledging the pain caused by the wrongdoing. This step allows individuals to confront their emotions head-on and understand the impact of the offense. It’s crucial to remember that forgiving does not mean forgetting; rather, it is a conscious decision to release the grip of resentment.

Empathize with the Offender:

Empathy is a cornerstone of forgiveness. By putting ourselves in the shoes of the person who caused the hurt, we can gain insight into their motivations and struggles. Understanding that everyone is capable of making mistakes and causing harm helps humanize the offender, making forgiveness a more attainable goal. South Africa’s reconciliation process is a testament to the power of empathy in healing deep-seated wounds.

Altruistic Gift of Forgiveness:

The Altruistic Gift of Forgiveness involves recognizing our shared humanity. We all make mistakes and have hurt others at some point. Through the stages of guilt and gratitude, we come to understand the liberating power of forgiveness. This realization inspires us to give the gift of forgiveness to others, fostering a cycle of healing and compassion.

Commit Publicly to Forgive:

Public commitment adds a layer of accountability to the forgiveness process. By expressing forgiveness openly, whether through spoken words, a written letter, or a symbolic gesture, we solidify our commitment to letting go of resentment. This step not only aids personal healing but can also inspire others to embark on their journey of forgiveness.

Hold onto Forgiveness:

Holding onto forgiveness is a continuous process that requires resilience. Painful memories may resurface, but it’s crucial to distinguish them from harboring unforgiveness. The REACH Method acknowledges the challenges of maintaining forgiveness, offering guidance on navigating triggers and doubts. Understanding that forgiveness is a journey, not a destination, empowers individuals to persevere.

Benefits of Forgiveness:

Everett Worthington, with decades of experience studying forgiveness, highlights numerous benefits for the person who forgives. According to Worthington, the primary way forgiveness affects mental health is by lowering rumination—the constant replaying of negative events in our minds. This reduction in rumination leads to improved mental well-being and emotional health. Additionally, forgiveness has been linked to decreased stress, anxiety, and depression, contributing to an overall positive impact on one’s life.

As we navigate a world rife with conflicts, it’s essential to recognize the transformative power of forgiveness. The REACH Method, developed by clinical psychologist Everett Worthington, provides a structured approach to forgiving, offering a pathway to healing and reconciliation. Worthington’s decades of experience studying forgiveness underscore the profound impact it can have on individual and societal well-being.

Beyond personal benefits, forgiveness has the potential to reshape societies and bridge divides. Instead of responding to conflicts with weapons and troops, let us consider the humanity support that the REACH Method embodies—a powerful tool to address the root causes of strife and build a foundation for lasting peace.

By embracing forgiveness, we not only free ourselves from the burden of resentment but also pave the way for a more compassionate and harmonious world. As Everett Worthington aptly puts it, “There are a lot of benefits to the person who forgives.” Lowering rumination and improving mental health are just a few of the many rewards awaiting those who choose the path of forgiveness.

In a world hungry for healing and reconciliation, let us embrace the REACH Method and its transformative potential. Together, we can unlock the power of forgiveness and sow the seeds of peace for generations to come.

Link:https://peacelilysite.com/2024/02/22/the-healing-power-of-forgiveness-unlocking-peace-with-the-reach-method/

#Forgivness #Happiness #REACH #EverettWorthington

https://www.cnbc.com/2023/05/06/forgiveness-can-boost-happiness-improve-mental-health-how-to-start.html

Zero Limits: Clearing Negative Energy, Returning to Perfect Emptiness

The Secret Hawaiian System for Wealth, Health, Peace, and More

In 1984, a therapist in Hawaii achieved remarkable results over three years, healing mentally ill patients at the Hawaii State Hospital without resorting to clinical counseling or medication. Reviewing their records, he repeatedly recited four phrases to “clear” himself: “I’m sorry, please forgive me, thank you, I love you.”

This extraordinary tale intrigued Mr. Vitale, inspiring him to seek out this extraordinary therapist and learn from him. Vitale discovered that Dr. Hew Len employed these four sentences as part of a traditional Hawaiian healing technique known as “Hooponopono,” which translates to “to correct, to clear, to make right” in Hawaiian.

This method not only restored the health of mentally ill patients but also miraculously cured a woman who had suffered from asthma for 50 years overnight. Can four sentences really resolve all problems? Smooth out everything?

These four affirmations have the power to clear all negative energy, balance emotions, and enable you to return to the divine state of “zero limits” (a state of returning to zero, also known as emptiness in Buddhist philosophy, where nothing exists, and anything is possible). By embracing these four phrases, you can face your life more freely and elegantly, leading to health, wealth, and joy.

By approaching each day with an unrestricted perspective, repeating these four sentences concerning your mind, subconscious, experiences, people, and encountered problems with a sincere, repentant, and grateful heart, you will learn to love yourself, forgive yourself, and appreciate yourself. This practice will lead you to live a more fulfilling, wise, and abundant life.

Let us not only refrain from complaining but also say, “I love you!”

What is the Zero Limits method?

It’s straightforward—just four sentences: “I’m sorry, please forgive me, thank you, I love you.”

What do these four sentences represent? In simple terms:

“I’m sorry”: Acknowledge 100% responsibility for what has happened (because everything is created by oneself).

“Please forgive me”: Request forgiveness (forgive oneself).

“Thank you”: Express gratitude, show trust, and believe that all problems will be resolved in the best way for everyone involved.

“I love you”: Invoke the power of divinity to clear related memories and heal all wounds.

Although these four sentences in Ho’oponopono therapy are simple, they encompass profound states and meanings. This is a convenient method that can be used at any time during our spiritual growth journey, transcending various spiritual practices.

How to use this method? It’s straightforward—whenever you encounter a problem, simply keep repeating these sentences (there’s no need to rush into belief or doubt; give it a try).

Fundamental Theory of Zero Limits:

You are not aware of what is happening.

Whether consciously or unconsciously, it is impossible to be aware of everything happening within and around you. At this very moment, your body and brain are self-adjusting without your conscious awareness. Countless invisible signals are transmitted through the air, from radio waves to thoughts and consciousness. All of this occurs unconsciously, and your consciousness is not aware of nor in control of this process. This is why you can think positively but still face challenges. In essence, you must understand that your consciousness is not the true creator of everything.

You cannot control everything

If you are unaware of what is happening, you certainly cannot control it. Believing that the world follows your commands is merely a manifestation of satisfying the desires of the ego. Since your ego cannot completely comprehend what is happening in the world, allowing the ego to decide what is best for you is obviously unwise. You can make choices, but you cannot control. You can use your consciousness to choose what you want to experience, but you must also learn to let go and not worry about how or when it will happen; surrender is the key.

You can heal everything that happens.

Regardless of what appears in your life and how it comes about, it requires healing. Because it is now within your perception, if you can feel it, you can heal it. If you see it in others and it troubles you, you must heal it. You may not understand why it appeared in your life or how it happened, but you can let go now. As you have become aware of it, the more you heal, the simpler it becomes to manifest your desires. By releasing blocked energy, you allow this energy to be used for other things.

You must take 100% responsibility for everything you experience.

The events in your life are not your fault, but they are your responsibility. This responsibility includes everything said, done, and thought, as well as everything said, done, and thought by others appearing in your life. If you take 100% responsibility for everything in your life, then when others have problems, those problems also become yours. In short, you cannot blame anyone or anything for your current situation. All you can do is take responsibility, accept it, embrace it, and love it. The deeper you heal, the more connected you become to the source of life.

The ticket to the state of Zero Limits is saying “I love you.”

To overcome the bottleneck of understanding, to obtain a pass from healing to manifestation, is that simple phrase “I love you.” Saying “I love you” to divinity clears everything within you, allowing you to experience the miracle of “Zero Limits.” The key is to love all things: love the excess fat, love the hidden pain, love the troublesome issues, love children with problems, or love neighbors and partners—in short, love everything. Love transforms and releases blocked energy, and by saying “I love you,” you can experience the power of divinity, just like saying “Open sesame.”

Inspiration is more important than thought.

Thoughts are toys of the mind, while inspiration is a directive from divinity. From a certain point onward, you will surrender and learn to listen instead of begging and waiting. Thought is an attempt by the ego to control life from a limited perspective, while inspiration is a reception of messages from divinity and taking action. Thought yields results, while inspiration produces miracles.

Even if you are not sure what is happening, you can still solve problems.

A part of the purpose of survival is to solve problems. To solve problems, you must first understand: Who am I? Who is actually in charge? The consciousness thinks that intellect is the problem solver, capable of controlling what happens, what one experiences, and when. However, in reality, decisions are made before the consciousness decides, and intellect is unaware of this. If it is not intellect or consciousness, then who is in charge?

It is your subconscious. The subconscious is dominated by replayed memories, and it imitates, repeats, and resonates with these memories. The actions, understanding, feelings, and decisions of the subconscious are entirely dictated by memory. Similarly, consciousness operates through replayed memories without awareness. Therefore, replayed memories dominate everything the subconscious and consciousness experience.

The subconscious is the repository of accumulated memories since the beginning. It constantly replays past memories, and the power of choice that consciousness possesses is the power to choose. Both the subconscious and consciousness do not create their own thoughts, feelings, or actions; rather, their experiences resonate with replayed memories and inspirations.

To solve problems, it is crucial to understand that the physical body and the world itself are not the issue; the problem lies in the replayed memories within the subconscious.

The universe comes from nothing and will return to nothing. The universe begins at zero and ends at zero.

Zero Limits: Clearing Negative Energy, Returning to Perfect Emptiness

Link:https://peacelilysite.com/2024/02/02/zero-limits-clearing-negative-energy-returning-to-perfect-emptiness/

#SecretHawaiianSystem #Wealth #Health#Peace #ZeroLimits #NegativeEnergy #Forgiveness #Grateful #Thanks